<?xml version="1.0" encoding="UTF-8"?> <!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2d1 20170631//EN" "JATS-journalpublishing1.dtd"> <ArticleSet> <Article> <Journal> <PublisherName>jmedicalcasereports</PublisherName> <JournalTitle>Frontiers in Medical Case Reports</JournalTitle> <PISSN>I</PISSN> <EISSN>S</EISSN> <Volume-Issue>Volume 2; Issue 3</Volume-Issue> <PartNumber/> <IssueTopic>Multidisciplinary</IssueTopic> <IssueLanguage>English</IssueLanguage> <Season>(May-Jun, 2021)</Season> <SpecialIssue>N</SpecialIssue> <SupplementaryIssue>N</SupplementaryIssue> <IssueOA>Y</IssueOA> <PubDate> <Year>-0001</Year> <Month>11</Month> <Day>30</Day> </PubDate> <ArticleType>Medical Case Reports</ArticleType> <ArticleTitle>Cardiac Complication in A Woman with Mixed Connective Tissue Disease</ArticleTitle> <SubTitle/> <ArticleLanguage>English</ArticleLanguage> <ArticleOA>Y</ArticleOA> <FirstPage>1</FirstPage> <LastPage>7</LastPage> <AuthorList> <Author> <FirstName>Chen Yiwen</FirstName> <LastName/> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>N</CorrespondingAuthor> <ORCID/> <FirstName>Xia</FirstName> <LastName>Shudong</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> </Author> </AuthorList> <DOI/> <Abstract>Mixed connective tissue disease (MCTD) is a rare condition characterized by the presence of high-titer autoantibodies anti-U1 ribonucleoprotein (RNP) which symptoms are overlapped and varied. MCTD presentation in heart is not typical. Patients with cardiac complication may present with ventricular hypertrophy, abnormal heart conduction and pericarditis. We herein report a rare presentation of MCTD in a 62-year-old woman who had prominent cardiac symptoms. Echocardiogram demonstrated right ventricular enlargement, slight pericardial effusion, Holter ECG monitoring revealed cardiac arrhythmia. The patient was given methylprednisolone, Lei Gongteng, mycophenolate mofetil and recovery was apparent.</Abstract> <AbstractLanguage>English</AbstractLanguage> <Keywords>Mixed Connective Tissue Disease,Pericardial Effusion,Ventricular Enlargement</Keywords> <URLs> <Abstract>https://jmedicalcasereports.org/ubijournal-v1copy/journals/abstract.php?article_id=9611&title=Cardiac Complication in A Woman with Mixed Connective Tissue Disease</Abstract> </URLs> <References> <ReferencesarticleTitle>References</ReferencesarticleTitle> <ReferencesfirstPage>16</ReferencesfirstPage> <ReferenceslastPage>19</ReferenceslastPage> <References>Faden A, Aljamili A, Aljamili A, Alahmari S, Asiri A. Mixed connective tissue disease in young Saudi patient with recurrent dental abscess: A case report. Int J Health Sci (Qassim) 2018; 12: 65-68. Fukushima M, Shiba T, Yoshimura S, Doi H, Nambu M. Myocarditis in a girl with mixed connective tissue disease. Pediatr Int 2018; 60: 478-479. Lundberg IE. Cardiac involvement in autoimmune myositis and mixed connective tissue disease. Lupus 2005; 14: 708-712. Nakamura H, Tateishi S, Kawakami A, Ida H, Fukuda T, Sasaki M, Koide Y, Ashizawa N, Seto S, Hayashi T, Sato S. A case of mixed connective tissue disease complicated with hypertrophic obstructive cardiomyopathy. Rheumatol Int 2008; 28: 1273-1275. Ortega-Hernandez OD and Shoenfeld Y. Mixed connective tissue disease: an overview of clinical manifestations, diagnosis and treatment. Best Pract Res Clin Rheumatol 2012; 26: 61-72. Sapkota B and Al Khalili Y. Mixed Connective Tissue Disease. StatPearls. Treasure Island (FL): StatPearls Publishing Copyright © 2021, StatPearls Publishing LLC.; 2021. Tani C, Carli L, Vagnani S, Talarico R, Baldini C, Mosca M, Bombardieri S. The diagnosis and classification of mixed connective tissue disease. J Autoimmun 2014; 48: 46-49. Triantafyllias K, de Blasi M, Land;uuml;tgendorf F, Cavagna L, Stortz M, Weinmann-Menke J, Konstantinides S, Galle PR, Schwarting A. High cardiovascular risk in mixed connective tissue disease: evaluation of macrovascular involvement and its predictors by aortic pulse wave velocity. Clin Exp Rheumatol 2019; 37: 994-1002.</References> </References> </Journal> </Article> </ArticleSet>