<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2d1 20170631//EN" "JATS-journalpublishing1.dtd">
      <JournalTitle>Frontiers in Medical Case Reports</JournalTitle>
      <Volume-Issue>Volume 2; Issue 2</Volume-Issue>
      <Season>(Mar-Apr, 2021)</Season>
      <ArticleType>Medical Case Reports</ArticleType>
      <ArticleTitle>Type 1 Myringoplasty and Platelet Gel Surgical Approach: A Case Report</ArticleTitle>
          <FirstName>A. F.</FirstName>
      <Abstract>Tympanoplasty is indicated to repair tympanic membrane perforations in patients affected by hearing loss. We investigated the outcomes of unconventional microscopic approach to type 1 tympanoplasty with autologous platelet gel in tympanic membrane perforation. Considering that platelet gel improves reparation of cutaneous lesions, we evaluate the efficacy of platelet gel application in patients with a damage of a particular soft tissue, as tympanic membrane (Adler and Kent, 2002; Bhanot and Alex, 2002; Mann et al., 2001; Pierce et al., 1991). We treated a patient referred to Otorinolaryngology Clinic of S. Maria del Carmine Hospital, Rovereto (TN) with a diagnosis of tympanic membrane perforation and mixed left hearing loss who undergone to a type 1 tympanoplasty with platelet gel. Our primary outcome was tympanic index closure. We report a faster recovery in this patient treated with platelet gel as an outpatients procedure. In conclusion, platelet gel application in otosurgery, in outpatients treatment. is a noninvasive, safe technique to restore tympanic perforation. However, further prospective data are needed to confirm these preliminary results.</Abstract>
      <Keywords>Type 1 Tympanoplasty,Autologous Platelet Gel,Tympanic Index Closure</Keywords>
        <Abstract>https://jmedicalcasereports.org/ubijournal-v1copy/journals/abstract.php?article_id=9494&amp;title=Type 1 Myringoplasty and Platelet Gel Surgical Approach: A Case Report</Abstract>
        <References>Adler SC and Kent KJ. Enhancing healing with growth factors. Facial Plast Surg Clin North Am 2002; 10: 129-146.&#13;
Bhanot S and Alex JC. Current applications of platelet gels in facial plastic surgery. Facial Plast Surg 2002;18: 27-33.&#13;
I-Kung Wu P, Diaz P, Borg-Stein J. Platelet-Rich Plasma. Phys Med Clin N Am 2016; 27: 825-853.&#13;
Mann D, Plosker H, Winland-Brown JE. The use of autologous platelet rich plasma (platelet gel) and autologous platelet poor plasma (fibrin glue) in cosmetic surgery. Plast Reconstr Surg 2001; 107: 229-237.&#13;
Pierce GF, Mustoe TA, Altrock BW, Deuel TF, Thomason A. Role of platelet derived growth factor in wound healing. J Cell Biochem 1991; 45: 319-326.&#13;
Zhang W, Guo Y, Kuss M, Shi W, Aldrich AL, Untrauer J, Kielian T, Duan B. Platelet-Rich Plasma for the Treatment of Tissue Infection: Preparation and Clinical Evaluation. Tissue Eng Part B Rev 2019; 25: 225–236.</References>