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      <JournalTitle>Frontiers in Medical Case Reports</JournalTitle>
      <Volume-Issue>Volume 2; Issue 2</Volume-Issue>
      <Season>(Mar-Apr, 2021)</Season>
      <ArticleType>Medical Case Reports</ArticleType>
      <ArticleTitle>Colonic Adenocarcinoma Diagnosed by Contrast-Enhanced Ultrasound Combined with Percutaneous Ultrasound-Guided Biopsy after Failed Endoscopic Biopsy: A Case Report</ArticleTitle>
      <Abstract>The pathological diagnosis of gastrointestinal masses may pose challenges to the gastroenterologist or surgeon as far as obtaining access and tissue diagnoses (Ballo and Guy, 2001). There are various types of colon tumors, including epithelial tumors (adenocarcinoma, adenosquamous carcinoma, undifferentiated carcinoma, etc.), mesenchymal tumors, and metastatic tumors. The treatment protocols are made according to the pathological type (Tarazona et al., 2020). Endoscopic biopsy is the most commonly used method for intestinal neoplasm (ASGE Standards of Practice Committee, 2010), but there are some limitations, such as discomfort in the examination process of patients with contraindications to anesthesia, difficulty in sampling due to the lesion morphology and regional necrosis. We present a case of colon adenocarcinoma diagnosed by contrast-enhanced ultrasound combined with percutaneous ultrasound-guided biopsy after failed endoscopic biopsy.</Abstract>
      <Keywords>Gastrointestinal Tumor,Biopsy,Ultrasound-Guided,Contrast-Enhanced Ultrasound</Keywords>
        <Abstract>https://jmedicalcasereports.org/ubijournal-v1copy/journals/abstract.php?article_id=9493&amp;title=Colonic Adenocarcinoma Diagnosed by Contrast-Enhanced Ultrasound Combined with Percutaneous Ultrasound-Guided Biopsy after Failed Endoscopic Biopsy: A Case Report</Abstract>
        <References>ASGE Standards of Practice Committee, Harrison ME, Anderson MA, Appalaneni V, Banerjee S, Ben-Menachem T, Cash BD, Fanelli RD, Fisher L, Fukami N, Gan SI, Ikenberry SO, Jain R, Khan K, Krinsky ML, Maple JT, Shen B, Van Guilder T, Baron TH, Dominitz JA . The role of endoscopy in the management of patients with known and suspected colonic obstruction and pseudo-obstruction. Gastrointest Endosc 2010; 71: 669-679.&#13;
Ballo MS and Guy CD. Percutaneous fine-needle aspiration of gastrointestinal wall lesions with image guidance. Diagn Cytopathol 2001; 24: 16-20.&#13;
Edwards BK, Ward E, Kohler BA, Eheman C, Zauber AG, Anderson RN, Jemal A, Schymura MJ, Lansdorp-Vogelaar I, Seeff LC, van Ballegooijen M, Goede SL, Ries LA. Annual report to the nation on the status of cancer, 1975–2006, featuring colorectal cancer trends and impact of interventions (risk factors, screening, and treatment) to reduce future rates. Cancer 2010; 116: 544-573.&#13;
Nakano S, Minaga K, Yamashita Y. Endoscopic ultrasound-guided fine-needle aspiration of sigmoid colon cancer undiagnosed with endoscopic biopsy. Arab J Gastroenterol 2019; 20: 209-210.&#13;
Sparchez Z, Radu P, Zaharia T, Kacso G, Grigorescu I, Botis G, Badea R. Usefulness of contrast enhanced ultrasound guidance in percutaneous biopsies of liver tumors. J Gastrointestin Liver Dis 2011; 20: 191-196.&#13;
Tarazona N, Roda D, Roselland;oacute; S, Huerta M, Cervantes A. New guidelines for optimal patient care with localized colon cancer: recommending what is proven, but also watching what research is bringing. Ann Oncol 2020; 31: 1287-1288.&#13;
Wei T, Lu M, Wang L, Jiang Z, Wu M, Li J, Hu Z, Cheng X, Li T, Zhang Z, Wu X, Tan B, Liao J. Contrast-Enhanced Ultrasound Guided Transoral Core Needle Biopsy: A Novel, Safe and Well-Tolerated Procedure for Obtaining High-Quality Tissue in Patients with Oral Cancer. Ultrasound Med Biol 2020; 46: 3210-3217.&#13;
Zhang X and Chen L. The recent progress of the mechanism and regulation of tumor necrosis in colorectal cancer. J Cancer Res Clin Oncol 2016; 142: 453-463.</References>