<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2d1 20170631//EN" "JATS-journalpublishing1.dtd">
      <JournalTitle>Frontiers in Medical Case Reports</JournalTitle>
      <Volume-Issue>Volume 1; Issue 4</Volume-Issue>
      <Season>(Jul-Aug, 2020)</Season>
      <ArticleType>Medical Case Reports</ArticleType>
      <ArticleTitle>Psychosis Induced by Isotretinoin: In an Adolescent Case</ArticleTitle>
      <Abstract>Acne vulgaris is common disease in adolescents. One of the drugs in the treatment algorithm is oral isotretinoin. Previously, psychotic conditions related to the use of oral isotretinoin have been reported in adults. A 16-year-old girl who presented with marked psychotic symptoms and completely recovered shortly after isotretinoin treatment was discontinued. Psychiatric symptoms may develop during isotretinoin treatment and should be considered in the planning of treatment and follow-up.</Abstract>
      <Keywords>Acne vulgaris,Isotretinoin,Psychosis</Keywords>
        <Abstract>https://jmedicalcasereports.org/ubijournal-v1copy/journals/abstract.php?article_id=7706&amp;title=Psychosis Induced by Isotretinoin: In an Adolescent Case</Abstract>
        <References>Barak Y, Wohl Y, Greenberg Y, Dayan YB, Friedman T, Shoval G, Knobler HY. Affective psychosis following Accutane (isotretinoin) treatment. International clinical sychopharmacology 2005; 20: 39-41.&#13;
Bremner JD, Shearer KD, McCaffery PJ. Retinoic acid and affective disorders: the evidence for an association. J Clin Psychiatry 2012; 73: 37-50.&#13;
Fornaro M. Obsessive-compulsive disorder with bipolar diathesis following isotretinoin therapy remitting upon treatment with olanzapine and fluvoxamine. Neuropsychiatr Dis Treat 2010; 6: 719-722.&#13;
Kontaxakis VP, Skourides D, Ferentinos P, Havaki-Kontaxaki BJ, Papadimitriou GN. Isotretinoin and psychopathology: a review. Ann Gen Psychia 2009; 8: 2.&#13;
Lucca JM, Varghese NA, Ramesh M, Ram D. A Case Report of Isotretinoin-induced Manic Psychosis. Indian Journal of Dermatology 2016; 61: 120.&#13;
Maude Ludot, Stephane Mouchabac, Florian Ferrer. Inter-relationships between isotretinoin treatment and psychiatric disorders: Depression, bipolar disorder, anxiety, psychosis and suicide risks. World J Psychiatr 2015; 5: 222-227.&#13;
Schaffer LC, Schaffer CB, Hunter S, Miller A. Psychiatric reactions to isotretinoin in patients with bipolar disorder. J Affect Disord 2010; 122: 306-308.&#13;
Simi? D, Situm M, Letica E, Penavi? JZ, Zivkovi? MV, Tomi T. Psychological impact of isotretinoin treatment in patients with moderate and severe acne. Coll Antropol 2009; 33: 15-19&#13;
Sundararajan Rajagopal. Acute psychosis induced by isotretinoin. Indian Journal of Psychiatry 2014; 56: 295.</References>