<?xml version="1.0" encoding="UTF-8"?> <!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2d1 20170631//EN" "JATS-journalpublishing1.dtd"> <ArticleSet> <Article> <Journal> <PublisherName>jmedicalcasereports</PublisherName> <JournalTitle>Frontiers in Medical Case Reports</JournalTitle> <PISSN>I</PISSN> <EISSN>S</EISSN> <Volume-Issue>Volume 5; Issue 4</Volume-Issue> <PartNumber/> <IssueTopic>Multidisciplinary</IssueTopic> <IssueLanguage>English</IssueLanguage> <Season>(Jul-Aug, 2024)</Season> <SpecialIssue>N</SpecialIssue> <SupplementaryIssue>N</SupplementaryIssue> <IssueOA>Y</IssueOA> <PubDate> <Year>-0001</Year> <Month>11</Month> <Day>30</Day> </PubDate> <ArticleType>Medical Case Reports</ArticleType> <ArticleTitle>Late-Onset Warfarin-Induced Skin Hemorrhagic Bullae and Spontaneous Intramural Hematomas of The Gastrointestinal Tract</ArticleTitle> <SubTitle/> <ArticleLanguage>English</ArticleLanguage> <ArticleOA>Y</ArticleOA> <FirstPage>1</FirstPage> <LastPage>6</LastPage> <AuthorList> <Author> <FirstName>Segenet Bizuneh</FirstName> <LastName>Mengistu</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>N</CorrespondingAuthor> <ORCID/> <FirstName>Suleiman Ayalew</FirstName> <LastName>Belaym</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> <FirstName>Fikadu Alemiye</FirstName> <LastName>Molla</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> <FirstName>Rediet Getu</FirstName> <LastName>Degu</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> <FirstName>Alazar Wogayehu</FirstName> <LastName>Gebrehana</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> <FirstName>Biniam Yoannes</FirstName> <LastName>Wotango</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> </Author> </AuthorList> <DOI/> <Abstract>This case report describes a 62-year-old female with a history of ischemic heart disease and atrial fibrillation on long-term warfarin therapy who presented with gastrointestinal bleeding and unusual skin manifestations. This report highlights the potential for late-onset warfarin-induced skin hemorrhagic bullae and spontaneous intramural hematoma of the gastrointestinal tract (SIHGT), underscoring the need for vigilance in patients on anticoagulation therapy.</Abstract> <AbstractLanguage>English</AbstractLanguage> <Keywords>Warfarin,Skin Necrosis,Hemorrhagic Bullae,Intramural Hematoma,Gastrointestinal Tract,Anticoagulation Therapy</Keywords> <URLs> <Abstract>https://jmedicalcasereports.org/ubijournal-v1copy/journals/abstract.php?article_id=15353&title=Late-Onset Warfarin-Induced Skin Hemorrhagic Bullae and Spontaneous Intramural Hematomas of The Gastrointestinal Tract</Abstract> </URLs> <References> <ReferencesarticleTitle>References</ReferencesarticleTitle> <ReferencesfirstPage>16</ReferencesfirstPage> <ReferenceslastPage>19</ReferenceslastPage> <References>Bircher AJ, Harr T, Hohenstein L, Tsakiris DA. Hypersensitivity reactions to anticoagulant drugs: diagnosis and management options. 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