<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2d1 20170631//EN" "JATS-journalpublishing1.dtd">
<ArticleSet>
<Article>
<Journal>
<PublisherName>jmedicalcasereports</PublisherName>
<JournalTitle>Frontiers in Medical Case Reports</JournalTitle>
<PISSN>I</PISSN>
<EISSN>S</EISSN>
<Volume-Issue>Volume 1; Issue 1, (Jan-Jun,2020)</Volume-Issue>
<PartNumber/>
<IssueTopic>Multidisciplinary</IssueTopic>
<IssueLanguage>English</IssueLanguage>
<Season>Cancer Case Reports</Season>
<SpecialIssue>N</SpecialIssue>
<SupplementaryIssue>N</SupplementaryIssue>
<IssueOA>Y</IssueOA>
<PubDate>
<Year>-0001</Year>
<Month>11</Month>
<Day>30</Day>
</PubDate>
<ArticleType>Cancer Case Reports</ArticleType>
<ArticleTitle>A Rare Case of T- cell Lymphoma Found in the Liver</ArticleTitle>
<SubTitle/>
<ArticleLanguage>English</ArticleLanguage>
<ArticleOA>Y</ArticleOA>
<FirstPage>1</FirstPage>
<LastPage>6</LastPage>
<AuthorList>
<Author>
<FirstName>Neethi</FirstName>
<LastName>Dasu</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>N</CorrespondingAuthor>
<ORCID/>
<FirstName>Kailash</FirstName>
<LastName>Lal</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>Lucy</FirstName>
<LastName>Joo</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>Donald</FirstName>
<LastName>McMahon</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
</Author>
</AuthorList>
<DOI/>
<Abstract>Peripheral T-cell lymphomas, a group of non-Hodgkin lymphomas, are rare and aggressive neoplasms which usually portend a poor prognosis. In this case report, we present a 65-year-old male patient with rapidly progressing peripheral T-cell lymphoma found in his liver and spleen. He initially presented with elevated liver enzymes with initial tests failing to reveal a clear etiology. A liver biopsy revealed malignant infiltration with a peripheral T-Cell lymphoma. This case is important for practitioners to keep in mind rarer causes of hepatic dysfunction, as swift and careful evaluations to establish accurate diagnoses and initiate treatment is critical to improving outcomes.</Abstract>
<AbstractLanguage>English</AbstractLanguage>
<Keywords>T- Cell Lymphoma,Liver Biopsy,Neoplasms</Keywords>
<URLs>
<Abstract>https://jmedicalcasereports.org/ubijournal-v1copy/journals/abstract.php?article_id=15128&title=A Rare Case of T- cell Lymphoma Found in the Liver</Abstract>
</URLs>
<References>
<ReferencesarticleTitle>References</ReferencesarticleTitle>
<ReferencesfirstPage>16</ReferencesfirstPage>
<ReferenceslastPage>19</ReferenceslastPage>
<References>Campo E, Swerdlow SH, Harris NL, Pileri S, Stein H, Jaffe ES. The 2008 WHO classification of lymphoid neoplasms and beyond: evolving concepts and practical applications. Blood 2011; 117(19): 5019-5032.
Swerdlow SH, Campo E, Pileri SA, et al. The 2016 revision of the World Health Organization classification of lymphoid neoplasms. Blood 2016; 127(20): 2375-2390.
Adams SV, Newcomb PA, Shustov AR. Racial Patterns of Peripheral T-Cell Lymphoma Incidence and Survival in the United States. Journal of Clinical Oncology 2016; 34(9): 963-971.
Weisenburger DD, Savage KJ, Harris NL, Gascoyne RD, Jaffe ES, MacLennan KA, Rand;uuml;diger T, Pileri S, Nakamura S, Nathwani B, Campo E. Peripheral T-cell lymphoma, not otherwise specified: a report of 340 cases from the International Peripheral T-cell Lymphoma Project. Blood 2011; 117(12): 3402-3408.
Hastrup N, Ralfkiaer E, Pallesen G. Aberrant phenotypes in peripheral T cell lymphomas. Journal of Clinical Pathology 1989; 42(4): 398-402.
Pinkus GS, Ohara CJ, Said JW. Peripheral/post-thymic T-cell lymphomas: A spectrum of disease clinical, pathologic, and immunologic features of 78 cases. Cancer 1990; 65(4): 971-998.
Armitage JO, Weisenburger DD. New approach to classifying non-Hodgkinand;#39;s lymphomas: clinical features of the major histologic subtypes. Non-Hodgkinand;#39;s Lymphoma Classification Project. J Clin Oncol 1998; 16: 2780.
Medeiros LJ, Lardelli P, Stetler-Stevenson M, Longo DL, Jaffe ES. Genotypic Analysis of Diffuse, Mixed Cell Lymphomas: Comparisons with Morphologic and Immunophenotypic Findings. American journal of clinical pathology 1991; 95(4): 547-555.
A clinical evaluation of the International Lymphoma Study Group classification of non-Hodgkinand;#39;s lymphoma. The Non-Hodgkinand;#39;s Lymphoma Classification Project. Blood 1997; 89: 3909.
Abramson JS, Feldman T, Kroll-Desrosiers AR, Muffly LS, Winer E, Flowers CR, Lansigan F, Nabhan C, Nastoupil LJ, Nath R, Goy A. Peripheral T-cell lymphomas in a large US multicenter cohort: prognostication in the modern era including impact of frontline therapy. Annals of Oncology 2014; 25(11): 2211-2217.
Schlegelberger B, Himmler A, Godde E, Grote W, Feller AC, Lennert K. Cytogenetic findings in peripheral T-cell lymphomas as a basis for distinguishing low-grade and high-grade lymphomas. Blood 1994; 83(2): 505-511.
Ong ST, Le Beau MM. Chromosomal abnormalities and molecular genetics of non-Hodgkinand;#39;s lymphoma. Semin Oncol 1998; 25: 447.
Hartmann S, Gesk S, Scholtysik R, Kreuz M, Bug S, Vater I, Dand;ouml;ring C, Cogliatti S, Parrens M, Merlio JP, Kwiecinska A. High resolution SNP array genomic profiling of peripheral T cell lymphomas, not otherwise specified, identifies a subgroup with chromosomal aberrations affecting the REL locus. British journal of haematology 2010; 148(3): 402-412.
Zhang Y, Xu W, Liu H, Li J. Therapeutic options in peripheral T cell lymphoma. Journal of hematology and; oncology 2016; 9(1): 37.</References>
</References>
</Journal>
</Article>
</ArticleSet>