<?xml version="1.0" encoding="UTF-8"?> <!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2d1 20170631//EN" "JATS-journalpublishing1.dtd"> <ArticleSet> <Article> <Journal> <PublisherName>jmedicalcasereports</PublisherName> <JournalTitle>Frontiers in Medical Case Reports</JournalTitle> <PISSN>I</PISSN> <EISSN>S</EISSN> <Volume-Issue>Volume 4; Issue 5</Volume-Issue> <PartNumber/> <IssueTopic>Multidisciplinary</IssueTopic> <IssueLanguage>English</IssueLanguage> <Season>(Sep-Oct, 2023)</Season> <SpecialIssue>N</SpecialIssue> <SupplementaryIssue>N</SupplementaryIssue> <IssueOA>Y</IssueOA> <PubDate> <Year>-0001</Year> <Month>11</Month> <Day>30</Day> </PubDate> <ArticleType>Medical Case Reports</ArticleType> <ArticleTitle>Pregnancy and Lactation Associated Osteoporosis: A Case Report</ArticleTitle> <SubTitle/> <ArticleLanguage>English</ArticleLanguage> <ArticleOA>Y</ArticleOA> <FirstPage>1</FirstPage> <LastPage>8</LastPage> <AuthorList> <Author> <FirstName>Hadil</FirstName> <LastName>Basma</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>N</CorrespondingAuthor> <ORCID/> <FirstName>Sara</FirstName> <LastName>Dbouk</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> <FirstName>Zeinab</FirstName> <LastName>Issa</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> </Author> </AuthorList> <DOI/> <Abstract>Pregnancy and lactation associated osteoporosis (PLO) is an uncommon condition that may present with fragility fractures occurring during pregnancy or the post-partum period. Here, we report a case of 37-year-old woman who presented for lower back pain that started in her third trimester. Her body mass index (BMI) was 22.4, her menarche was at the age of 14 years, and she had no family history of osteoporosis. She sustained several vertebral fractures in her second month postpartum while lactating and then diagnosed with PLO. She was treated with teriparatide for two years. This is the first case of PLO reported in Lebanon to our knowledge. PLO should be suspected in pregnant women with back pain during pregnancy and the postpartum period. Stopping breastfeeding, supplementation with calcium and vitamin D, and treatment with anti-osteoporotic medications are the mainstays of the management of PLO.</Abstract> <AbstractLanguage>English</AbstractLanguage> <Keywords>Osteoporosis,Pregnancy,Lactation</Keywords> <URLs> <Abstract>https://jmedicalcasereports.org/ubijournal-v1copy/journals/abstract.php?article_id=14873&title=Pregnancy and Lactation Associated Osteoporosis: A Case Report</Abstract> </URLs> <References> <ReferencesarticleTitle>References</ReferencesarticleTitle> <ReferencesfirstPage>16</ReferencesfirstPage> <ReferenceslastPage>19</ReferenceslastPage> <References>Butscheidt S, Tsourdi E, Rolvien T, Delsmann A, Stand;uuml;rznickel J, Barvencik F, Jakob F, Hofbauer LC, Mundlos S, Kornak U, Seefried L, Oheim R. Relevant genetic variants are common in women with pregnancy and lactation-associated osteoporosis (PLO) and predispose to more severe clinical manifestations. Bone 2021; 147: 115911. Carsote M, Turturea MR, Valea A, Buescu C, Nistor C, Turturea IF. Bridging the Gap: Pregnancy-And Lactation-Associated Osteoporosis. Diagnostics (Basel) 2023; 13: 1615. Hadji P, Boekhoff J, Hahn M, Hellmeyer L, Hars O, Kyvernitakis I. Pregnancy-associated osteoporosis: a case-control study. Osteoporos Int 2017; 28: 1393-1399. Kovacs CS, Ralston SH. Presentation and management of osteoporosis presenting in association with pregnancy or lactation. Osteoporos Int 2015; 26: 2223-2241. Kovacs CS. Maternal Mineral and Bone Metabolism During Pregnancy, Lactation, and Post-Weaning Recovery. Physiol Rev 2016; 96: 449-547. Laroche M, Talibart M, Cormier C, Roux C, Guggenbuhl P, Degboe Y. Pregnancy-related fractures: a retrospective study of a French cohort of 52 patients and review of the literature. Osteoporos Int 2017; 28: 3135-3142. NORDIN BE, ROPER A. Post-pregnancy osteoporosis; a syndrome? Lancet 1955; 268: 431-434. Qian Y, Wang L, Yu L, Huang W. Pregnancy- and lactation-associated osteoporosis with vertebral fractures: a systematic review. BMC Musculoskelet Disord 2021; 22: 926. Sanz-Salvador L, Garcand;iacute;a-Pand;eacute;rez Mand;Aacute;, Tarand;iacute;n JJ, Cano A. Bone metabolic changes during pregnancy: A period of vulnerability to osteoporosis and fracture. Eur J Endocrinol 2015; 172: R53-R65.</References> </References> </Journal> </Article> </ArticleSet>