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  <Article>
    <Journal>
      <PublisherName>jmedicalcasereports</PublisherName>
      <JournalTitle>Frontiers in Medical Case Reports</JournalTitle>
      <PISSN>I</PISSN>
      <EISSN>S</EISSN>
      <Volume-Issue>Volume 4; Issue 1</Volume-Issue>
      <PartNumber/>
      <IssueTopic>Multidisciplinary</IssueTopic>
      <IssueLanguage>English</IssueLanguage>
      <Season>(Jan-Feb, 2023)</Season>
      <SpecialIssue>N</SpecialIssue>
      <SupplementaryIssue>N</SupplementaryIssue>
      <IssueOA>Y</IssueOA>
      <PubDate>
        <Year>-0001</Year>
        <Month>11</Month>
        <Day>30</Day>
      </PubDate>
      <ArticleType>Clinical Case Reports</ArticleType>
      <ArticleTitle>Eosinophilic Ulcer: Report of Four Clinical Cases</ArticleTitle>
      <SubTitle/>
      <ArticleLanguage>English</ArticleLanguage>
      <ArticleOA>Y</ArticleOA>
      <FirstPage>1</FirstPage>
      <LastPage>8</LastPage>
      <AuthorList>
        <Author>
          <FirstName>Julie Campos da Costa</FirstName>
          <LastName>Bastos</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>N</CorrespondingAuthor>
          <ORCID/>
          <FirstName>Giovanna Ressiguier</FirstName>
          <LastName>Peixoto</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
          <FirstName>Juliana Batista</FirstName>
          <LastName>Alvarenga</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
          <FirstName>Letícia Rodrigues</FirstName>
          <LastName>Crespo</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
          <FirstName>Maria Eduarda Barbosa</FirstName>
          <LastName>Lugon</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
          <FirstName>Thaís Gama de</FirstName>
          <LastName>Oliveira</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
          <FirstName>William Rodrigues da</FirstName>
          <LastName>Silva</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
          <FirstName>Alessandra Oliveira Ferrari</FirstName>
          <LastName>Gomes</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
          <FirstName>Silvia Paula de</FirstName>
          <LastName>Oliveira</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
          <FirstName>José de Assis Silva</FirstName>
          <LastName>Júnior</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
          <FirstName>Luisa Aguirre</FirstName>
          <LastName>Buexm</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
        </Author>
      </AuthorList>
      <DOI/>
      <Abstract>Unique histopathological type of chronic traumatic ulceration of the oral mucosa is the chronic inflammatory process with ulceration and eosinophilia, which may exhibit a pseudo invasive deep inflammatory reaction and regresses slowly. Interestingly, many of these lesions resolve after an incisional biopsy. The aim of this paper is to report four clinical cases of eosinophilic ulcers, with emphasis on an appropriate diagnosis by biopsy. In the four cases reported, an incisional biopsy was chosen because the lesions presented clinical characteristics of a probable squamous cell carcinoma, which was discarded after the surgical procedure and histopathological analysis. The performance of biopsy in cases of eosinophilic ulcer is essential for a correct diagnosis since the lesion resembles malignancies and other conditions.</Abstract>
      <AbstractLanguage>English</AbstractLanguage>
      <Keywords>Eosinophilic Ulcer,Diagnosis,Biopsy,Squamous Cell Carcinoma</Keywords>
      <URLs>
        <Abstract>https://jmedicalcasereports.org/ubijournal-v1copy/journals/abstract.php?article_id=14283&amp;title=Eosinophilic Ulcer: Report of Four Clinical Cases</Abstract>
      </URLs>
      <References>
        <ReferencesarticleTitle>References</ReferencesarticleTitle>
        <ReferencesfirstPage>16</ReferencesfirstPage>
        <ReferenceslastPage>19</ReferenceslastPage>
        <References>Bortoluzzi MC, Passador-Santos F, Capella DL, Manfro G, Nodari RJ Jr, Presta AA. Eosinophilic ulcer of oral mucosa: a case report. Ann Stomatol 2012; 3: 11-13.&#13;
&#13;
Damevska K, Gocev G, Nikolovska S. Eosinophilic ulcer of the oral mucosa: report of a case with multiple synchronous lesions. Am J Dermatopathol 2014; 36: 594-596.&#13;
&#13;
Dhanrajani P, Cropley PW. Oral eosinophilic or traumatic ulcer: A case report and brief review. Natl J Maxillofac Surg 2015; 6: 237-240.&#13;
&#13;
Didona D, Paolino G, Donati M, Didona B, Calvieri S. Eosinophilic ulcer of the tongue – Case report. An Bras Dermato l2015; 90: 88-90.&#13;
&#13;
Fonseca FP, de Andrade BAB, Coletta RD, Vargas PA, Lopes MA, de Almeida OP, Santos-Silva AR. Clinicopathological and immunohistochemical analysis of 19 cases of oral eosinophilic ulcers. Oral Surg Oral Med Oral Pathol Oral Radiol 2013; 115: 532-540.&#13;
&#13;
Gonand;ccedil;ales ES, Rubira-Bullen IF, Rubira CMF, Miyazawa M, Chinellato LEM, Consolaro A. Eosinophilic ulcer of the oral mucosa versus squamous cell carcinoma. Quintessence Int 2007; 38: 677-680.&#13;
&#13;
INCA - Instituto Nacional de Cand;acirc;ncer. 2022, Diagnand;oacute;stico precoce do cand;acirc;ncer de boca, Rio de Janeiro: INCA.&#13;
&#13;
Neville BW, Damm D, Allen CM, Chi AC. 2016, Patologia Oral e Maxilofacial, 4th edn, Rio de Janeiro: Elsevier.&#13;
&#13;
Regezi JA, Sciubba JJ, Jordan RCK. 2017, Patologia oral: correlaand;ccedil;and;otilde;es clinicopatoland;oacute;gicas, 7th edn, Rio de Janeiro: Elsevier.&#13;
&#13;
Shen WR, Chang JY, Wu YC, Cheng SJ, Chen HM, Wang YP. Oral traumatic ulcerative granuloma with stromal eosinophilia: a clinicopathological study of 34 cases. J Formos Med Assoc 2015; 114: 881-885.&#13;
&#13;
Song CH, Kim JY, Chi SG, Lee WJ, Lee SJ, Kim DW, Kim BS. Losing a tongue tip from an eosinophilic ulcer of the oral mucosa. J Dermatol 2011; 38: 1017-1019.&#13;
&#13;
Vand;eacute;lez A, Alamillos FJ, Dean A, Rodas J, Acosta A. Eosinophilic ulcer of the oral mucosa: report of a recurrent case on the tongue. Clin Exp Dermatol 1997; 22: 154-156.&#13;
&#13;
Woo SB. 2017, Oral pathology: a comprehensive atlas and text, 2nd edn, Philadelphia: Elsevier.</References>
      </References>
    </Journal>
  </Article>
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