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FRONTIERS IN MEDICAL CASE REPORTS - Volume 1; Issue 4, (Jul-Aug, 2020)

Pages: 1-08

Hemophagocytic Lymphohistiocytosis Associated with Sarcoidosis: A Case Report and Review of the Literature

Korkor Sackey, Dana Angelini

Category: Medical Case Reports

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Hemophagocytic lymphohistiocytosis (HLH) is a rare and often fatal inflammatory syndrome characterized by histiocyte proliferation and hemophagocytosis. Primary HLH primarily occurs in children and is caused by genetic mutations. Secondary HLH, more often seen in adults, occurs as a result of infections, malignancies or rarely rheumatic diseases. HLH secondary to sarcoidosis is rare. We present a case of HLH associated with recently diagnosed sarcoidosis in a 61-year-old female.

Keywords: Hemophagocytic lymphohistiocytosis, Sarcoidosis, Histiocyte proliferation


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