<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2d1 20170631//EN" "JATS-journalpublishing1.dtd">
<ArticleSet>
  <Article>
    <Journal>
      <PublisherName>jmedicalcasereports</PublisherName>
      <JournalTitle>Frontiers in Medical Case Reports</JournalTitle>
      <PISSN>I</PISSN>
      <EISSN>S</EISSN>
      <Volume-Issue>Volume 2; Issue 2</Volume-Issue>
      <PartNumber/>
      <IssueTopic>Multidisciplinary</IssueTopic>
      <IssueLanguage>English</IssueLanguage>
      <Season>(Mar-Apr, 2021)</Season>
      <SpecialIssue>N</SpecialIssue>
      <SupplementaryIssue>N</SupplementaryIssue>
      <IssueOA>Y</IssueOA>
      <PubDate>
        <Year>-0001</Year>
        <Month>11</Month>
        <Day>30</Day>
      </PubDate>
      <ArticleType>Medical Case Reports</ArticleType>
      <ArticleTitle>Ovarian Metastasis of Breast Cancer Found During Ovarian Tissue Cryopreservation for Fertility Preservation: A Case Report</ArticleTitle>
      <SubTitle/>
      <ArticleLanguage>English</ArticleLanguage>
      <ArticleOA>Y</ArticleOA>
      <FirstPage>1</FirstPage>
      <LastPage>5</LastPage>
      <AuthorList>
        <Author>
          <FirstName>Fabien</FirstName>
          <LastName>KRIEF</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>N</CorrespondingAuthor>
          <ORCID/>
          <FirstName>Charlotte</FirstName>
          <LastName>SONIGO</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
          <FirstName>Michael</FirstName>
          <LastName>GRYNBERG</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
        </Author>
      </AuthorList>
      <DOI/>
      <Abstract>We present the case of a patient with ovarian metastasis of breast cancer revealed during ovarian tissue cryopreservation for fertility preservation in an University Hospital. The patient was a twenty-eight years old woman with a breast cancer had a laparoscopy for ovarian tissue cryopreservation. Ovaries revealed normal aspect on CT scan and during laparoscopy. Unexpectedly, pathological analysis of ovarian tissue revealed a breast cancer metastasis within the cortex, while the medulla was sane. This case report confirms the possible complexity of organizing optimal oncologic management and fertility preservation under time pressure.</Abstract>
      <AbstractLanguage>English</AbstractLanguage>
      <Keywords>Oncofertility,Ovarian Tissue Cryopreservation,Breast Cancer,Ovarian Metastasis,Fertility Preservation</Keywords>
      <URLs>
        <Abstract>https://jmedicalcasereports.org/ubijournal-v1copy/journals/abstract.php?article_id=9575&amp;title=Ovarian Metastasis of Breast Cancer Found During Ovarian Tissue Cryopreservation for Fertility Preservation: A Case Report</Abstract>
      </URLs>
      <References>
        <ReferencesarticleTitle>References</ReferencesarticleTitle>
        <ReferencesfirstPage>16</ReferencesfirstPage>
        <ReferenceslastPage>19</ReferenceslastPage>
        <References>APHP. Rand;eacute;fand;eacute;rentiel de Prand;eacute;servation de la Fertilitand;eacute;. 2018. Disponible sur: https://www.aphp.fr/contenu/referentiel-preservation-de-la-fertilite-feminine&#13;
&#13;
Bastings L, Beerendonk CC, Westphal JR, Massuger LF, Kaal SE, Van Leeuwen FE, Braat DD, Peek R. Autotransplantation of cryopreserved ovarian tissue in cancer survivors and the risk of reintroducing malignancy: A systematic review. Human reproduction update 2013; 19: 483-506.&#13;
&#13;
Bedoschi G, Navarro PA, Oktay K. Chemotherapy-induced damage to ovary: mechanisms and clinical impact. Future Oncol 2016; 12: 2333?2344.&#13;
&#13;
Bigorie V, Morice P, Duvillard P, Antoine M, Cortez A, Flejou JF, Uzan S, Darai E, Barranger E. Ovarian metastases from breast cancer. Cancer 2010; 116: 799?804.&#13;
&#13;
Bloom JR, Stewart SL, Chang S, Banks PJ. Then and now: quality of life of young breast cancer survivors. Psychooncology 2004; 13: 147?160.&#13;
&#13;
DeSantis CE, Bray F, Ferlay J, Lortet-Tieulent J, Anderson BO, Jemal A. International Variation in Female Breast Cancer Incidence and Mortality Rates. Cancer Epidemiol Biomarkers Prev 2015; 24:1495?506.&#13;
&#13;
Donnez J and Dolmans MM. Fertility Preservation in Women. Campion EW, and;eacute;diteur. N Engl J Med 2017; 377: 1657?1665.&#13;
&#13;
Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer 2015; 136: E359-E386.&#13;
&#13;
Hashimoto T, Nakamura Y, Obata R, Doshida M, Toya M, Takeuchi T, Kyono K. Effects of fertility preservation in patients with breast cancer: A retrospective two?centers study. Reprod Med Biol 2017; 16: 374?379.&#13;
&#13;
Lambertini M, Goldrat O, Clatot F, Demeestere I, Awada A. Controversies about fertility and pregnancy issues in young breast cancer patients: current state of the art. Curr Opin Oncol 2017; 29: 243-252.&#13;
&#13;
Letourneau JM, Ebbel EE, Katz PP, Katz A, Ai WZ, Chien AJ, Melisko ME, Cedars MI, Rosen MP. Pretreatment fertility counseling and fertility preservation improve quality of life in reproductive age women with cancer. Cancer 2012; 118: 1710?1717.&#13;
&#13;
Oktay K, Harvey BE, Partridge AH, Quinn GP, Reinecke J, Taylor HS, Wallace WH, Wang ET, Loren AW. Fertility Preservation in Patients with Cancer: ASCO Clinical Practice Guideline Update. J Clin Oncol Off J Am Soc Clin Oncol 2018; 36: 1994?2001.&#13;
&#13;
Partridge AH, Ruddy KJ, Gelber S, Schapira L, Abusief M, Meyer M, Ginsburg E. Ovarian reserve in women who remain premenopausal after chemotherapy for early stage breast cancer. Fertil Steril 2010; 94: 638?644.&#13;
&#13;
Perrotin F, Marret H, Bouquin R, Fischer-Perrotin N, Lansac J, Body G. Incidence, diagnosis and prognosis of ovarian metastasis in breast cancer. Gynecol Obstet Fertil 2001; 29: 308?315.&#13;
&#13;
Peters IT, van der Steen MA, Huisman BW, Hilders CG, Smit VT, Vahrmeijer AL, Sier CF, Trimbos JB, Kuppen PJ. Morphological and phenotypical features of ovarian metastases in breast cancer patients. BMC Cancer 2017; 17: 206.&#13;
&#13;
Pimentel C, Becquet M, Lavoue V, Henno S, Leveque J, Ouldamer L. Ovarian Metastases from Breast Cancer: A Series of 28 Cases. Anticancer Res 2016; 36: 4195?4200.&#13;
&#13;
Practice Committee of American Society for Reproductive Medicine. Fertility preservation in patients undergoing gonadotoxic therapy or gonadectomy: a committee opinion. Fertil Steril 2013; 100: 1214?1223.&#13;
&#13;
Rosendahl M, Schmidt KT, Ernst E, Rasmussen PE, Loft A, Byskov AG, Andersen AN, Andersen CY. Cryopreservation of ovarian tissue for a decade in Denmark: a view of the technique. Reprod Biomed Online 2011; 22: 162?171.&#13;
&#13;
Sallem A, Shore J, Ray-Coquard I, Ferreux L, Bourdon M, Maignien C, Patrat C, Wolf JP, Pocate-Cheriet K. Fertility preservation in women with cancer: a national study about French oncologists awareness, experience, and feelings. J Assist Reprod Genet 2018; 35: 1843?1850.</References>
      </References>
    </Journal>
  </Article>
</ArticleSet>